Skip to content

motifbreakR

Updated by Hongjiang & ChatGPT on 02/19/2023

(2016, Bioinfo.)motifbreakR: An R/Bioconductor package for predicting variant effects at transcription factor binding sites

Vignette

bioconductor

The motifbreakR package is a popular R package used for identifying and analyzing DNA sequence motifs and their potential breaking (i.e., mutation or deletion) in various biological contexts. The package provides a suite of tools for detecting sequence mutations and deletions in DNA motifs, which can be used in fields such as genetics, genomics, and bioinformatics.

Below is a more detailed guide on using the motifbreakR package, along with some code examples to illustrate each step.

Step1: Install and load the motifbreakR package

First, you need to install the motifbreakR package from CRAN. You can do this using the following command:

R
if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("GO.db") # If you need to
BiocManager::install("motifbreakR")

Once you have installed the package, you can load it into your R session using the following command:

R
library(motifbreakR)